Dementia Risk Factor Review Project

The Dementia Risk Factor Review Project commenced in 2005 to determine the impact of risk factors such as health and lifestyle on cognitive function in both late and middle-adulthood. This project involves conducting a series of systematic reviews on modifiable risk factors for Alzheimer’s disease, vascular dementia, mild cognitive impairment and cognitive decline in normal ageing. We have completed reviews on smoking¹ , serum cholesterol² and alcohol consumption, and are presently undertaking reviews in relation to body weight. This project is conducted in conjunction with the Dementia Collaborative Research Centre led by Associate Professor Marc Budge from Geriatric Medicine, ANU.

RESEARCH HIGHLIGHT

Forest plot showing the effect of current smoking as a risk factor for Alzheimer's disease

ARU staff working on the Dementia Risk Factor Review Project

• Dr Holly Mack
• Associate Professor Kaarin Anstey
• Dr Nicolas Cherbuin
• Jennifer Young

References

1. Anstey, K.J., von Sanden, C., Salim, A., & O'Kearney, R. (2007). Smoking as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis. American Journal of Epidemiology. Published Online. doi: 10.1093/ajekwm116.

2. Anstey, K.J., Lipnicki, D.M., & Low, L. (2008). Cholesterol as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies. American Journal of American Journal of Geriatric Psychiatry, 16, 343-354.